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Firing rate homeostasis counteracts changes in stability of recurrent neural networks caused by synapse loss in Alzheimer’s disease
The impairment of cognitive function in Alzheimer’s disease is clearly correlated to synapse loss. However, the mechanisms underlying this correlation are only poorly understood. Here, we investigate how the loss of excitatory synapses in sparsely connected random networks of spiking excitatory and...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505475/ https://www.ncbi.nlm.nih.gov/pubmed/32841234 http://dx.doi.org/10.1371/journal.pcbi.1007790 |