Multiple Wnts act synergistically to induce Chk1/Grapes expression and mediate G2 arrest in Drosophila tracheoblasts

Larval tracheae of Drosophila harbour progenitors of the adult tracheal system (tracheoblasts). Thoracic tracheoblasts are arrested in the G2 phase of the cell cycle in an ATR (mei-41)-Checkpoint Kinase1 (grapes, Chk1) dependent manner prior to mitotic re-entry. Here we investigate developmental reg...

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Detalles Bibliográficos
Autores principales: Kizhedathu, Amrutha, Kunnappallil, Rose Sebastian, Bagul, Archit V, Verma, Puja, Guha, Arjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505655/
https://www.ncbi.nlm.nih.gov/pubmed/32876044
http://dx.doi.org/10.7554/eLife.57056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505655/
https://www.ncbi.nlm.nih.gov/pubmed/32876044
http://dx.doi.org/10.7554/eLife.57056

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