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Multiple Wnts act synergistically to induce Chk1/Grapes expression and mediate G2 arrest in Drosophila tracheoblasts
Larval tracheae of Drosophila harbour progenitors of the adult tracheal system (tracheoblasts). Thoracic tracheoblasts are arrested in the G2 phase of the cell cycle in an ATR (mei-41)-Checkpoint Kinase1 (grapes, Chk1) dependent manner prior to mitotic re-entry. Here we investigate developmental reg...
Autores principales: | Kizhedathu, Amrutha, Kunnappallil, Rose Sebastian, Bagul, Archit V, Verma, Puja, Guha, Arjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505655/ https://www.ncbi.nlm.nih.gov/pubmed/32876044 http://dx.doi.org/10.7554/eLife.57056 |
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