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Localized Induction of Gene Expression in Embryonic Stem Cell Aggregates Using Holographic Optical Tweezers to Create Biochemical Gradients

Three-dimensional (3D) cell models that mimic the structure and function of native tissues are enabling more detailed study of physiological and pathological mechanisms in vitro. We have previously demonstrated the ability to build and manipulate 3D multicellular microscopic structures using hologra...

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Detalles Bibliográficos
Autores principales: Kirkham, Glen R, Ware, James, Upton, Thomas, Allen, Stephanie, Shakesheff, Kevin M, Buttery, Lee DK
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505830/
https://www.ncbi.nlm.nih.gov/pubmed/33029554
http://dx.doi.org/10.1007/s40883-019-00114-5