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Arsenic trioxide enhances the chemotherapeutic efficiency of cisplatin in cholangiocarcinoma cells via inhibiting the 14-3-3ε-mediated survival mechanism

Cholangiocarcinoma (CCA) is the second most frequent primary liver carcinoma with high degrees of malignancy and mortality. Chemotherapy plays a key role in the treatment of CCA, however, the low chemotherapeutic efficiency leads to a bottleneck. So unraveling the potential mechanisms to enhance the...

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Detalles Bibliográficos
Autores principales: Jin, Ming, Wu, Liunan, Chen, Shuai, Cai, Rong, Dai, Yi, Yang, Haojun, Tang, Liming, Li, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505839/
https://www.ncbi.nlm.nih.gov/pubmed/33024577
http://dx.doi.org/10.1038/s41420-020-00330-x