Tobacco Smoke and Inhaled Drugs Alter Expression and Activity of Multidrug Resistance-Associated Protein-1 (MRP1) in Human Distal Lung Epithelial Cells in vitro

Multidrug resistance-associated protein-1 (MRP1/ABCC1) is highly expressed in human lung tissues. Recent studies suggest that it significantly affects the pulmonary disposition of its substrates, both after pulmonary and systemic administration. To better understand the molecular mechanisms involved...

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Detalles Bibliográficos
Autores principales: Selo, Mohammed Ali, Delmas, Anne-Sophie, Springer, Lisa, Zoufal, Viktoria, Sake, Johannes A., Clerkin, Caoimhe G., Huwer, Hanno, Schneider-Daum, Nicole, Lehr, Claus-Michael, Nickel, Sabrina, Langer, Oliver, Ehrhardt, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505930/
https://www.ncbi.nlm.nih.gov/pubmed/33015009
http://dx.doi.org/10.3389/fbioe.2020.01030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505930/
https://www.ncbi.nlm.nih.gov/pubmed/33015009
http://dx.doi.org/10.3389/fbioe.2020.01030

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