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Celastrol Efficacy by Oral Administration in the Adjuvant-Induced Arthritis Model

Background: We previously demonstrated that celastrol has significant anti-inflammatory and bone protective effects when administered via the intraperitoneal route. For further preclinical evaluation, an effective oral administration of celastrol is crucial. Here we aimed to study the therapeutic do...

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Detalles Bibliográficos
Autores principales: Cascão, Rita, Vidal, Bruno, Carvalho, Tânia, Lopes, Inês Pascoal, Romão, Vasco C., Goncalves, João, Moita, Luis Ferreira, Fonseca, João Eurico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505947/
https://www.ncbi.nlm.nih.gov/pubmed/33015082
http://dx.doi.org/10.3389/fmed.2020.00455