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Regulation of MicroRNA-497-Targeting AKT2 Influences Tumor Growth and Chemoresistance to Cisplatin in Lung Cancer

BACKGROUND: MicroRNA-497 (miR-497) has been implicated in several cancers. Increasing studies demonstrate the role of AKT2 in cancers as an oncogene which is closely associated with tumor aggressiveness by enhancing cancer cell survival, migration and invasion However, miR-497/AKT2 axis in non-small...

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Detalles Bibliográficos
Autores principales: Wang, Lin, Ji, Xiang-Bo, Wang, Li-Hong, Qiu, Jian-Ge, Zhou, Feng-Mei, Liu, Wen-Jing, Wan, Di-di, Lin, Marie Chai-mi, Liu, Ling-Zhi, Zhang, Jian-Ying, Jiang, Bing-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505950/
https://www.ncbi.nlm.nih.gov/pubmed/33015042
http://dx.doi.org/10.3389/fcell.2020.00840