AMPK Activity Contributes to G2 Arrest and DNA Damage Decrease via p53/p21 Pathways in Oxidatively Damaged Mouse Zygotes

In zygotes, the capacity of G2/M checkpoint and DNA repair mechanisms to respond to DNA damage varies depending on different external stressors. In our previous studies, we found that mild oxidative stress induced a G2/M phase delay in mouse zygotes fertilized in vitro, due to the activation of the...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Pei, Li, Zhiling, Xu, Feng, Ru, Gaizhen, Huang, Yue, Lin, En, Peng, Sanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505953/
https://www.ncbi.nlm.nih.gov/pubmed/33015052
http://dx.doi.org/10.3389/fcell.2020.539485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505953/
https://www.ncbi.nlm.nih.gov/pubmed/33015052
http://dx.doi.org/10.3389/fcell.2020.539485

Ejemplares similares