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AMPK Activity Contributes to G2 Arrest and DNA Damage Decrease via p53/p21 Pathways in Oxidatively Damaged Mouse Zygotes

In zygotes, the capacity of G2/M checkpoint and DNA repair mechanisms to respond to DNA damage varies depending on different external stressors. In our previous studies, we found that mild oxidative stress induced a G2/M phase delay in mouse zygotes fertilized in vitro, due to the activation of the...

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Detalles Bibliográficos
Autores principales:	He, Pei, Li, Zhiling, Xu, Feng, Ru, Gaizhen, Huang, Yue, Lin, En, Peng, Sanfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505953/ https://www.ncbi.nlm.nih.gov/pubmed/33015052 http://dx.doi.org/10.3389/fcell.2020.539485

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