Astrocyte Glutamate Uptake and Signaling as Novel Targets for Antiepileptogenic Therapy

Astrocytes regulate and respond to extracellular glutamate levels in the central nervous system (CNS) via the Na(+)-dependent glutamate transporters glutamate transporter-1 (GLT-1) and glutamate aspartate transporter (GLAST) and the metabotropic glutamate receptors (mGluR) 3 and mGluR5. Both impaire...

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Detalles Bibliográficos
Autores principales: Peterson, Allison R., Binder, Devin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505989/
https://www.ncbi.nlm.nih.gov/pubmed/33013665
http://dx.doi.org/10.3389/fneur.2020.01006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505989/
https://www.ncbi.nlm.nih.gov/pubmed/33013665
http://dx.doi.org/10.3389/fneur.2020.01006

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