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Astrocyte Glutamate Uptake and Signaling as Novel Targets for Antiepileptogenic Therapy
Astrocytes regulate and respond to extracellular glutamate levels in the central nervous system (CNS) via the Na(+)-dependent glutamate transporters glutamate transporter-1 (GLT-1) and glutamate aspartate transporter (GLAST) and the metabotropic glutamate receptors (mGluR) 3 and mGluR5. Both impaire...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505989/ https://www.ncbi.nlm.nih.gov/pubmed/33013665 http://dx.doi.org/10.3389/fneur.2020.01006 |