The combined effect of obesity and aging on human sperm DNA methylation signatures: inclusion of BMI in the paternal germ line age prediction model

Male aging and obesity have both been shown to contribute to declines in fertility in men. Recent work in aging has shown consistent epigenetic changes to sperm as a man ages. In fact, our lab has built a tool that utilizes DNA methylation signatures from sperm to effectively predict an individual’s...

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Detalles Bibliográficos
Autores principales: Salas-Huetos, Albert, James, Emma R., Broberg, Dallin S., Aston, Kenneth I., Carrell, Douglas T., Jenkins, Timothy G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506015/
https://www.ncbi.nlm.nih.gov/pubmed/32958862
http://dx.doi.org/10.1038/s41598-020-71979-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506015/
https://www.ncbi.nlm.nih.gov/pubmed/32958862
http://dx.doi.org/10.1038/s41598-020-71979-8

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