Cargando…

Ruthenium (II) complex cis-[Ru(II)(ŋ(2)-O(2)CC(7)H(7)O(2))(dppm)(2)]PF(6)-hmxbato induces ROS-mediated apoptosis in lung tumor cells producing selective cytotoxicity

Ruthenium complexes have been extensively explored as potential molecules for cancer treatment. Considering our previous findings on the remarkable cytotoxic activity exhibited by the ruthenium (II) complex 3-hydroxy-4-methoxybenzoate (hmxbato)-cis-[Ru(II)(ŋ(2)-O(2)CC(7)H(7)O(2))(dppm)(2)]PF(6) agai...

Descripción completa

Detalles Bibliográficos
Autores principales: Costa, Mônica Soares, Gonçalves, Yasmim Garcia, Borges, Bruna Cristina, Silva, Marcelo José Barbosa, Amstalden, Martin Krähenbühl, Costa, Tássia Rafaella, Antunes, Lusânia Maria Greggi, Rodrigues, Renata Santos, Rodrigues, Veridiana de Melo, de Faria Franca, Eduardo, Zoia, Mariana Alves Pereira, de Araújo, Thaise Gonçalves, Goulart, Luiz Ricardo, Von Poelhsitz, Gustavo, Yoneyama, Kelly Aparecida Geraldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506019/
https://www.ncbi.nlm.nih.gov/pubmed/32958783
http://dx.doi.org/10.1038/s41598-020-72420-w