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Ruthenium (II) complex cis-[Ru(II)(ŋ(2)-O(2)CC(7)H(7)O(2))(dppm)(2)]PF(6)-hmxbato induces ROS-mediated apoptosis in lung tumor cells producing selective cytotoxicity
Ruthenium complexes have been extensively explored as potential molecules for cancer treatment. Considering our previous findings on the remarkable cytotoxic activity exhibited by the ruthenium (II) complex 3-hydroxy-4-methoxybenzoate (hmxbato)-cis-[Ru(II)(ŋ(2)-O(2)CC(7)H(7)O(2))(dppm)(2)]PF(6) agai...
Autores principales: | Costa, Mônica Soares, Gonçalves, Yasmim Garcia, Borges, Bruna Cristina, Silva, Marcelo José Barbosa, Amstalden, Martin Krähenbühl, Costa, Tássia Rafaella, Antunes, Lusânia Maria Greggi, Rodrigues, Renata Santos, Rodrigues, Veridiana de Melo, de Faria Franca, Eduardo, Zoia, Mariana Alves Pereira, de Araújo, Thaise Gonçalves, Goulart, Luiz Ricardo, Von Poelhsitz, Gustavo, Yoneyama, Kelly Aparecida Geraldo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506019/ https://www.ncbi.nlm.nih.gov/pubmed/32958783 http://dx.doi.org/10.1038/s41598-020-72420-w |
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