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Internal Ribosome Entry Sites Mediate Cap-Independent Translation of Bmi1 in Nasopharyngeal Carcinoma

Bmi1 is overexpressed in multiple human cancers. We previously reported the oncogenic function and the transcription regulation mechanisms of Bmi1 in nasopharyngeal carcinoma (NPC). In this study, we observed that the mRNA and the protein levels of Bmi1 were strictly inconsistent in NPC cell lines a...

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Detalles Bibliográficos
Autores principales: Wang, Hongbo, Zhu, Yunjia, Hu, Lijuan, Li, Yangyang, Liu, Guihong, Xia, Tianliang, Xiong, Dan, Luo, Yiling, Liu, Binliu, An, Yu, Li, Manzhi, Huang, Yuehua, Zhong, Qian, Zeng, Musheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506037/
https://www.ncbi.nlm.nih.gov/pubmed/33014838
http://dx.doi.org/10.3389/fonc.2020.01678