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Development and Validation of CRISPR Activator Systems for Overexpression of CB1 Receptors in Neurons

Gene therapy approaches using viral vectors for the overexpression of target genes have been for several years the focus of gene therapy research against neurological disorders. These approaches deliver robust expression of therapeutic genes, but are typically limited to the delivery of single genes...

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Detalles Bibliográficos
Autores principales: Di Maria, Valentina, Moindrot, Marine, Ryde, Martin, Bono, Antonino, Quintino, Luis, Ledri, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506083/
https://www.ncbi.nlm.nih.gov/pubmed/33013319
http://dx.doi.org/10.3389/fnmol.2020.00168