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Recapitulation of Human Embryonic Heartbeat to Promote Differentiation of Hepatic Endoderm to Hepatoblasts

Hepatic development requires multiple sequential physicochemical environmental changes in an embryo, and human pluripotent stem cells (hPSCs) allow for the elucidation of this embryonic developmental process. However, the current in vitro methods for hPSC-hepatic differentiation, which employ variou...

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Detalles Bibliográficos
Autores principales: Yoshimoto, Koki, Minier, Nicolas, Yang, Jiandong, Imamura, Satoshi, Stocking, Kaylene, Patel, Janmesh, Terada, Shiho, Hirai, Yoshikazu, Kamei, Ken-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506096/
https://www.ncbi.nlm.nih.gov/pubmed/33015019
http://dx.doi.org/10.3389/fbioe.2020.568092