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Recapitulation of Human Embryonic Heartbeat to Promote Differentiation of Hepatic Endoderm to Hepatoblasts
Hepatic development requires multiple sequential physicochemical environmental changes in an embryo, and human pluripotent stem cells (hPSCs) allow for the elucidation of this embryonic developmental process. However, the current in vitro methods for hPSC-hepatic differentiation, which employ variou...
Autores principales: | Yoshimoto, Koki, Minier, Nicolas, Yang, Jiandong, Imamura, Satoshi, Stocking, Kaylene, Patel, Janmesh, Terada, Shiho, Hirai, Yoshikazu, Kamei, Ken-ichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506096/ https://www.ncbi.nlm.nih.gov/pubmed/33015019 http://dx.doi.org/10.3389/fbioe.2020.568092 |
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