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UPLC-MS/MS Measurement of the Effect of Isavuconazole, Itraconazole and Fluconazole on the Pharmacokinetics of Selinexor in Rats

OBJECTIVE: An ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method for the determination of selinexor was established to investigate the effects of isavuconazole, itraconazole and fluconazole on the pharmacokinetics of selinexor in rats, respectively. METHODS: Twenty-...

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Detalles Bibliográficos
Autores principales: Li, Shuang-long, Zhang, Yi, Cheng, Qian-shi, Xin, Jun-zhe, Dong, Ze-qin, Qiu, Xiang-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506178/
https://www.ncbi.nlm.nih.gov/pubmed/32982330
http://dx.doi.org/10.2147/IDR.S269831