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In silico hippocampal modeling for multi-target pharmacotherapy in schizophrenia

Treatment of schizophrenia has had limited success in treating core cognitive symptoms. The evidence of multi-gene involvement suggests that multi-target therapy may be needed. Meanwhile, the complexity of schizophrenia pathophysiology and psychopathology, coupled with the species-specificity of muc...

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Detalles Bibliográficos
Autores principales: Sherif, Mohamed A., Neymotin, Samuel A., Lytton, William W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506542/
https://www.ncbi.nlm.nih.gov/pubmed/32958782
http://dx.doi.org/10.1038/s41537-020-00109-0