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Luteolin modulates SERCA2a via Sp1 upregulation to attenuate myocardial ischemia/reperfusion injury in mice

The sarco/endoplasmic reticulum Ca(2+) ATPase 2a (SERCA2a) is responsible for calcium transport during excitation–contraction coupling and is essential for maintaining myocardial systolic/diastolic function and intracellular Ca(2+) levels. Therefore, it is important to investigate mechanisms whereby...

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Detalles Bibliográficos
Autores principales: Hu, Ya, Zhang, Chengmeng, Zhu, Hong, Wang, Shuai, Zhou, Yao, Zhao, Jiaqi, Xia, Yong, Li, Dongye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506543/
https://www.ncbi.nlm.nih.gov/pubmed/32958799
http://dx.doi.org/10.1038/s41598-020-72325-8