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Luteolin modulates SERCA2a via Sp1 upregulation to attenuate myocardial ischemia/reperfusion injury in mice
The sarco/endoplasmic reticulum Ca(2+) ATPase 2a (SERCA2a) is responsible for calcium transport during excitation–contraction coupling and is essential for maintaining myocardial systolic/diastolic function and intracellular Ca(2+) levels. Therefore, it is important to investigate mechanisms whereby...
Autores principales: | Hu, Ya, Zhang, Chengmeng, Zhu, Hong, Wang, Shuai, Zhou, Yao, Zhao, Jiaqi, Xia, Yong, Li, Dongye |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506543/ https://www.ncbi.nlm.nih.gov/pubmed/32958799 http://dx.doi.org/10.1038/s41598-020-72325-8 |
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