DNA methylation across the genome in aged human skeletal muscle tissue and muscle-derived cells: the role of HOX genes and physical activity

Skeletal muscle tissue demonstrates global hypermethylation with age. However, methylome changes across the time-course of differentiation in aged human muscle derived cells, and larger coverage arrays in aged muscle tissue have not been undertaken. Using 850K DNA methylation arrays we compared the...

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Detalles Bibliográficos
Autores principales: Turner, D. C., Gorski, P. P., Maasar, M. F., Seaborne, R. A., Baumert, P., Brown, A. D., Kitchen, M. O., Erskine, R. M., Dos-Remedios, I., Voisin, S., Eynon, N., Sultanov, R. I., Borisov, O. V., Larin, A. K., Semenova, E. A., Popov, D. V., Generozov, E. V., Stewart, C. E., Drust, B., Owens, D. J., Ahmetov, I. I., Sharples, A. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506549/
https://www.ncbi.nlm.nih.gov/pubmed/32958812
http://dx.doi.org/10.1038/s41598-020-72730-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506549/
https://www.ncbi.nlm.nih.gov/pubmed/32958812
http://dx.doi.org/10.1038/s41598-020-72730-z

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