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Effect of pharmacokinetic/pharmacodynamic ratio on tigecycline clinical response and toxicity in critically ill patients with multidrug-resistant Gram-negative infections

INTRODUCTION: The information about the pharmacokinetics and optimal dose of tigecycline in critically ill patients with severe underlying diseases is limited and controversial. In this study, we evaluate the pharmacokinetic parameters of tigecycline in critically ill patients with multidrug-resista...

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Detalles Bibliográficos
Autores principales: Ruiz, Jesus, Ramirez, Paula, Villarreal, Esther, Gordon, Mónica, Sánchez, María Ángeles, Martín, María, Castellanos-Ortega, Álvaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506777/
https://www.ncbi.nlm.nih.gov/pubmed/32999720
http://dx.doi.org/10.1177/2050312120958897