Maintaining Myocardial Glucose Utilization in Diabetic Cardiomyopathy Accelerates Mitochondrial Dysfunction

Cardiac glucose uptake and oxidation are reduced in diabetes despite hyperglycemia. Mitochondrial dysfunction contributes to heart failure in diabetes. It is unclear whether these changes are adaptive or maladaptive. To directly evaluate the relationship between glucose delivery and mitochondrial dy...

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Detalles Bibliográficos
Autores principales: Wende, Adam R., Schell, John C., Ha, Chae-Myeong, Pepin, Mark E., Khalimonchuk, Oleh, Schwertz, Hansjörg, Pereira, Renata O., Brahma, Manoja K., Tuinei, Joseph, Contreras-Ferrat, Ariel, Wang, Li, Andrizzi, Chase A., Olsen, Curtis D., Bradley, Wayne E., Dell’Italia, Louis J., Dillmann, Wolfgang H., Litwin, Sheldon E., Abel, E. Dale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2020
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506832/
https://www.ncbi.nlm.nih.gov/pubmed/32366681
http://dx.doi.org/10.2337/db19-1057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506832/
https://www.ncbi.nlm.nih.gov/pubmed/32366681
http://dx.doi.org/10.2337/db19-1057

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