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Panax notoginseng saponins alleviates advanced glycation end product-induced apoptosis by upregulating SIRT1 and antioxidant expression levels in HUVECs

The present study examined whether Panax notoginseng saponins (PNS) alleviated advanced glycation end product (AGE)-induced apoptosis in human umbilical vein endothelial cells (HUVECs). HUVECs were incubated with 300 µg/ml AGEs alone or AGEs and PNS (0.05, 0.5 or 1 mg/ml) for 48 h. The results of th...

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Detalles Bibliográficos
Autores principales: Bo, Yang, Jian, Zhang, Zhi-Jun, Sun, Quing, Wu, Hua, Zhao, Chuan-Wei, Li, Yu-Kang, Cao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506886/
https://www.ncbi.nlm.nih.gov/pubmed/32973948
http://dx.doi.org/10.3892/etm.2020.9229