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Caveolae, CD109, and endothelial cells as targets for treating Alzheimer's disease
Reduced functionality of transforming growth factor β (TGF‐β) is a major pathogenetic component of Alzheimer's disease (AD). The reduction is caused by an ≈50% decrease in the AD brain of the TGF‐β receptor, TGFBR, causing a bottleneck effect that reduces the downstream actions of TGF‐β, which...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506987/ https://www.ncbi.nlm.nih.gov/pubmed/32995471 http://dx.doi.org/10.1002/trc2.12066 |