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Timeless couples G‐quadruplex detection with processing by DDX11 helicase during DNA replication

Regions of the genome with the potential to form secondary DNA structures pose a frequent and significant impediment to DNA replication and must be actively managed in order to preserve genetic and epigenetic integrity. How the replisome detects and responds to secondary structures is poorly underst...

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Detalles Bibliográficos
Autores principales: Lerner, Leticia K, Holzer, Sandro, Kilkenny, Mairi L, Šviković, Saša, Murat, Pierre, Schiavone, Davide, Eldridge, Cara B, Bittleston, Alice, Maman, Joseph D, Branzei, Dana, Stott, Katherine, Pellegrini, Luca, Sale, Julian E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506991/
https://www.ncbi.nlm.nih.gov/pubmed/32705708
http://dx.doi.org/10.15252/embj.2019104185