Metronomic chemotherapy offsets HIFα induction upon maximum‐tolerated dose in metastatic cancers

Conventional maximum‐tolerated dose (MTD) chemotherapy relies on periodic, massive cancer cell ablation events followed by treatment‐free intermissions, stereotypically resulting in resistance, relapse, and mortality. Furthermore, MTD chemotherapy can promote metastatic dissemination via activation...

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Detalles Bibliográficos
Autores principales: Schito, Luana, Rey, Sergio, Xu, Ping, Man, Shan, Cruz‐Muñoz, William, Kerbel, Robert S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507002/
https://www.ncbi.nlm.nih.gov/pubmed/32686360
http://dx.doi.org/10.15252/emmm.201911416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507002/
https://www.ncbi.nlm.nih.gov/pubmed/32686360
http://dx.doi.org/10.15252/emmm.201911416

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