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Metronomic chemotherapy offsets HIFα induction upon maximum‐tolerated dose in metastatic cancers
Conventional maximum‐tolerated dose (MTD) chemotherapy relies on periodic, massive cancer cell ablation events followed by treatment‐free intermissions, stereotypically resulting in resistance, relapse, and mortality. Furthermore, MTD chemotherapy can promote metastatic dissemination via activation...
Autores principales: | Schito, Luana, Rey, Sergio, Xu, Ping, Man, Shan, Cruz‐Muñoz, William, Kerbel, Robert S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507002/ https://www.ncbi.nlm.nih.gov/pubmed/32686360 http://dx.doi.org/10.15252/emmm.201911416 |
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