AAV9‐mediated AIRE gene delivery clears circulating antibodies and tissue T‐cell infiltration in a mouse model of autoimmune polyglandular syndrome type‐1

OBJECTIVES: Autoimmune polyglandular syndrome type‐1 (APS‐1) is a monogenic recessive disorder characterised by multiple endocrine abnormalities, chronic mucocutaneous candidiasis and high titres of serum autoantibodies. To date, no curative treatment is available; current therapies manage the sympt...

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Detalles Bibliográficos
Autores principales: Almaghrabi, Sarah, Azzouz, Mimoun, Tazi Ahnini, Rachid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507015/
https://www.ncbi.nlm.nih.gov/pubmed/32994995
http://dx.doi.org/10.1002/cti2.1166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507015/
https://www.ncbi.nlm.nih.gov/pubmed/32994995
http://dx.doi.org/10.1002/cti2.1166

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