Doxycycline preserves chondrocyte viability and function in human and calf articular cartilage ex vivo

Prolonging chondrocyte survival is essential to ensure fresh osteochondral (OC) grafts for treatment of articular cartilage lesions. Doxycycline has been shown to enhance cartilage growth, disrupt terminal differentiation of chondrocytes, and inhibit cartilage matrix degradation. It is unknown wheth...

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Detalles Bibliográficos
Autores principales: Yue, Li, Vuong, Brian, Yao, Hongwei, Owens, Brett D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507091/
https://www.ncbi.nlm.nih.gov/pubmed/32918797
http://dx.doi.org/10.14814/phy2.14571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507091/
https://www.ncbi.nlm.nih.gov/pubmed/32918797
http://dx.doi.org/10.14814/phy2.14571

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