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β-catenin mediates the effect of GLP-1 receptor agonist on ameliorating hepatic steatosis induced by high fructose diet

The hypoglycemic drug GLP-1 receptor agonist can ameliorate hepatic steatosis but the mechanism is not clear. Intake of high fructose leads to non-alcoholic fatty liver disease by stimulating lipid synthesis, and β-catenin is the key molecule for realizing GLP-1 function in extrahepatic tissues; wit...

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Detalles Bibliográficos
Autores principales: Gao, Zhe, Song, Guang-Yao, Ren, Lu-Ping, Ma, Hui-Juan, Ma, Bo-Qing, Chen, Shu-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507137/
https://www.ncbi.nlm.nih.gov/pubmed/32930541
http://dx.doi.org/10.4081/ejh.2020.3160