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β-catenin mediates the effect of GLP-1 receptor agonist on ameliorating hepatic steatosis induced by high fructose diet
The hypoglycemic drug GLP-1 receptor agonist can ameliorate hepatic steatosis but the mechanism is not clear. Intake of high fructose leads to non-alcoholic fatty liver disease by stimulating lipid synthesis, and β-catenin is the key molecule for realizing GLP-1 function in extrahepatic tissues; wit...
Autores principales: | Gao, Zhe, Song, Guang-Yao, Ren, Lu-Ping, Ma, Hui-Juan, Ma, Bo-Qing, Chen, Shu-Chun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PAGEPress Publications, Pavia, Italy
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507137/ https://www.ncbi.nlm.nih.gov/pubmed/32930541 http://dx.doi.org/10.4081/ejh.2020.3160 |
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