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Image‐guided mathematical modeling for pharmacological evaluation of nanomaterials and monoclonal antibodies

While plasma concentration kinetics has traditionally been the predictor of drug pharmacological effects, it can occasionally fail to represent kinetics at the site of action, particularly for solid tumors. This is especially true in the case of delivery of therapeutic macromolecules (drug‐loaded na...

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Detalles Bibliográficos
Autores principales: Dogra, Prashant, Butner, Joseph D., Nizzero, Sara, Ruiz Ramírez, Javier, Noureddine, Achraf, Peláez, María J., Elganainy, Dalia, Yang, Zhen, Le, Anh‐Dung, Goel, Shreya, Leong, Hon S., Koay, Eugene J., Brinker, C. Jeffrey, Cristini, Vittorio, Wang, Zhihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507140/
https://www.ncbi.nlm.nih.gov/pubmed/32314552
http://dx.doi.org/10.1002/wnan.1628