Cargando…

Image‐guided mathematical modeling for pharmacological evaluation of nanomaterials and monoclonal antibodies

While plasma concentration kinetics has traditionally been the predictor of drug pharmacological effects, it can occasionally fail to represent kinetics at the site of action, particularly for solid tumors. This is especially true in the case of delivery of therapeutic macromolecules (drug‐loaded na...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dogra, Prashant, Butner, Joseph D., Nizzero, Sara, Ruiz Ramírez, Javier, Noureddine, Achraf, Peláez, María J., Elganainy, Dalia, Yang, Zhen, Le, Anh‐Dung, Goel, Shreya, Leong, Hon S., Koay, Eugene J., Brinker, C. Jeffrey, Cristini, Vittorio, Wang, Zhihui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2020
Materias:	Advanced Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507140/ https://www.ncbi.nlm.nih.gov/pubmed/32314552 http://dx.doi.org/10.1002/wnan.1628

Ejemplares similares

A mathematical model to predict nanomedicine pharmacokinetics and tumor delivery
por: Dogra, Prashant, et al.
Publicado: (2020)

Mathematical modeling in cancer nanomedicine: a review
por: Dogra, Prashant, et al.
Publicado: (2019)

A mathematical model for the quantification of a patient’s sensitivity to checkpoint inhibitors and long-term tumour burden
por: Butner, Joseph D, et al.
Publicado: (2021)

Sequential deconstruction of composite drug transport in metastatic breast cancer
por: Goel, Shreya, et al.
Publicado: (2020)

Mathematical prediction of clinical outcomes in advanced cancer patients treated with checkpoint inhibitor immunotherapy
por: Butner, Joseph D., et al.
Publicado: (2020)

A modeling-based approach to optimize COVID-19 vaccine dosing schedules for improved protection
por: Dogra, Prashant, et al.
Publicado: (2023)

Dedifferentiation-mediated stem cell niche maintenance in early-stage ductal carcinoma in situ progression: insights from a multiscale modeling study
por: Butner, Joseph D., et al.
Publicado: (2022)

Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics
por: Dogra, Prashant, et al.
Publicado: (2018)

Innate immunity plays a key role in controlling viral load in COVID-19: mechanistic insights from a whole-body infection dynamics model
por: Dogra, Prashant, et al.
Publicado: (2020)

Innate Immunity Plays a Key Role in Controlling Viral Load in COVID-19: Mechanistic Insights from a Whole-Body Infection Dynamics Model
por: Dogra, Prashant, et al.
Publicado: (2020)

Translational Modeling Identifies Synergy between Nanoparticle-Delivered miRNA-22 and Standard-of-Care Drugs in Triple-Negative Breast Cancer
por: Dogra, Prashant, et al.
Publicado: (2022)

Protocol for mathematical prediction of patient response and survival to immune checkpoint inhibitor immunotherapy
por: Butner, Joseph D., et al.
Publicado: (2022)

Imaging-Based Subtypes of Pancreatic Ductal Adenocarcinoma Exhibit Differential Growth and Metabolic Patterns in the Pre-Diagnostic Period: Implications for Early Detection
por: Zaid, Mohamed, et al.
Publicado: (2020)

Mass Transport Model of Radiation Response: Calibration and Application to Chemoradiation for Pancreatic Cancer
por: Wang, Charles X., et al.
Publicado: (2022)

Exploring Cell Migration Mechanisms in Cancer: From Wound Healing Assays to Cellular Automata Models
por: Migliaccio, Giorgia, et al.
Publicado: (2023)

Theory and Experimental Validation of a Spatio-temporal Model of Chemotherapy Transport to Enhance Tumor Cell Kill
por: Wang, Zhihui, et al.
Publicado: (2016)

Do Pandemics Obey the Elliott Wave Principle of Financial Markets?
por: Dogra, Prashant, et al.
Publicado: (2021)

Is the worst of the COVID-19 global pandemic yet to come? Application of financial mathematics as candidate predictive tools
por: Dogra, Prashant, et al.
Publicado: (2021)

A Mathematical Model to Estimate Chemotherapy Concentration at the Tumor-Site and Predict Therapy Response in Colorectal Cancer Patients with Liver Metastases
por: Anaya, Daniel A., et al.
Publicado: (2021)

High throughput toxicity screening and intracellular detection of nanomaterials
por: Collins, Andrew R., et al.
Publicado: (2016)

Effects of food‐borne nanomaterials on gastrointestinal tissues and microbiota
por: Bouwmeester, Hans, et al.
Publicado: (2017)

Understanding the immunological interactions of engineered nanomaterials: Role of the bio‐corona
por: Fadeel, Bengt
Publicado: (2022)

A multiscale agent-based model of ductal carcinoma in situ
por: Butner, Joseph D., et al.
Publicado: (2019)

Photoresponsive Inorganic Nanomaterials in Oncology
por: Barbero, Francesco, et al.
Publicado: (2023)

Carbonaceous Nanomaterials for Phototherapy of Cancer
por: Gupta, Tanisha, et al.
Publicado: (2023)

Intracellular and extracellular targets as mechanisms of cancer therapy by nanomaterials in relation to their physicochemical properties
por: Andraos, Charlene, et al.
Publicado: (2020)

Predicting nanomaterials pulmonary toxicity in animals by cell culture models: Achievements and perspectives
por: Di Ianni, Emilio, et al.
Publicado: (2022)

Mammalian gastrointestinal tract parameters modulating the integrity, surface properties, and absorption of food‐relevant nanomaterials
por: Bellmann, Susann, et al.
Publicado: (2015)

Safe digital isolation of the santorini plexus during radical retropubic prostatectomy
por: Cristini, Cristiano, et al.
Publicado: (2013)

Immunotoxicity of nanomaterials in health and disease: Current challenges and emerging approaches for identifying immune modifiers in susceptible populations
por: Hofer, Sabine, et al.
Publicado: (2022)

Expanded clinical and experimental use of SOX11 - using a monoclonal antibody
por: Nordström, Lena, et al.
Publicado: (2012)

Production and characterisation of monoclonal antibodies against RAI3 and its expression in human breast cancer
por: Jörißen, Hannah, et al.
Publicado: (2009)

Localization of drug biodistribution in a 3D-bioengineered subcutaneous neovascularized microenvironment
por: Capuani, Simone, et al.
Publicado: (2022)

Diagnostic accuracy of monoclonal antibody based serum immunoglobulin free light chain immunoassays in myeloma cast nephropathy
por: Hutchison, Colin A, et al.
Publicado: (2012)

Intratumoral injection of hydrogel-embedded nanoparticles enhances retention in glioblastoma
por: Brachi, Giulia, et al.
Publicado: (2020)

Ceramide as an endothelial cell surface receptor and a lung-specific lipid vascular target for circulating ligands
por: Staquicini, Daniela I., et al.
Publicado: (2023)

Vasculature-Driven Biomechanical Deformable Image Registration of Longitudinal Liver Cholangiocarcinoma Computed Tomographic Scans
por: Cazoulat, Guillaume, et al.
Publicado: (2019)

Bridging the In Vitro to In Vivo gap: Using the Chick Embryo Model to Accelerate Nanoparticle Validation and Qualification for In Vivo studies
por: Butler, Kimberly S., et al.
Publicado: (2022)

Molecular targeting of FATP4 transporter for oral delivery of therapeutic peptide
por: Hu, Zhenhua, et al.
Publicado: (2020)

A modeling-based approach to optimize COVID-19 vaccine dosing schedules for improved protection
por: Dogra, Prashant, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_gek3dgiir59d0l2jmkenq93ou9