Respiratory safety of lemborexant in healthy adult and elderly subjects with mild obstructive sleep apnea: A randomized, double‐blind, placebo‐controlled, crossover study

Lemborexant is a dual orexin receptor antagonist indicated for the treatment of adult and elderly individuals with insomnia. Some current pharmacologic treatments for insomnia cause respiratory depression, a serious safety concern, particularly for individuals with obstructive sleep apnea (OSA). Thi...

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Detalles Bibliográficos
Autores principales: Cheng, Jocelyn Y., Filippov, Gleb, Moline, Margaret, Zammit, Gary K., Bsharat, Mohammad, Hall, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Sleep Disordered Breathing
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507183/
https://www.ncbi.nlm.nih.gov/pubmed/32187781
http://dx.doi.org/10.1111/jsr.13021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507183/
https://www.ncbi.nlm.nih.gov/pubmed/32187781
http://dx.doi.org/10.1111/jsr.13021

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