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The immunologic Warburg effect: Evidence and therapeutic opportunities in autoimmunity

Pro‐inflammatory signals induce metabolic reprogramming in innate and adaptive immune cells of both myeloid and lymphoid lineage, characterized by a shift to aerobic glycolysis akin to the Warburg effect first described in cancer. Blocking the switch to aerobic glycolysis impairs the survival, diffe...

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Detalles Bibliográficos
Autor principal: Kornberg, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507184/
https://www.ncbi.nlm.nih.gov/pubmed/32105390
http://dx.doi.org/10.1002/wsbm.1486