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Transfection of glycoprotein encoding mRNA for swift evaluation of N‐glycan engineering strategies

N‐glycosylation is defined as a key quality attribute for the majority of complex biological therapeutics. Despite many N‐glycan engineering efforts, the demand to generate desired N‐glycan profiles that may vary for different proteins in a reproducible manner is still difficult to fulfill in many c...

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Detalles Bibliográficos
Autores principales: Bydlinski, Nina, Coats, Michael T, Maresch, Daniel, Strasser, Richard, Borth, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507192/
https://www.ncbi.nlm.nih.gov/pubmed/32134190
http://dx.doi.org/10.1002/btpr.2990