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XBP1 negatively regulates CENPF expression via recruiting ATF6α to the promoter during ER stress

BACKGROUND: Centromere protein F (CENPF) is a key component of the kinetochore complex involved in mitosis, cell differentiation and cellular response to stresses. However, the alteration of CENPF in response to endoplasmic reticulum (ER) stress has not been well described. In the present study, we...

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Detalles Bibliográficos
Autores principales: Shen, Tao, Li, Yan, Liang, Shuang, Chen, Zhiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507253/
https://www.ncbi.nlm.nih.gov/pubmed/32973403
http://dx.doi.org/10.1186/s12935-020-01553-9