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Utility of plasma neurofilament light and total tau for clinical trials in Alzheimer's disease

INTRODUCTION: Several blood‐based biomarkers are associated with neuronal injury, but their utility in interventional clinical trials is unclear. This study retrospectively evaluated the utility of plasma neurofilament light (NfL) and total tau (t‐tau) in an 18‐month trial in mild Alzheimer's d...

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Detalles Bibliográficos
Autores principales: Raket, Lars Lau, Kühnel, Line, Schmidt, Ellen, Blennow, Kaj, Zetterberg, Henrik, Mattsson‐Carlgren, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507310/
https://www.ncbi.nlm.nih.gov/pubmed/32995466
http://dx.doi.org/10.1002/dad2.12099