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MT1‐MMP‐Activated Liposomes to Improve Tumor Blood Perfusion and Drug Delivery for Enhanced Pancreatic Cancer Therapy

Promoting tumor angiogenesis effectively and specifically to resolve tumor‐associated hypoperfusion holds promise for improving pancreatic cancer therapy. Herein, a doxorubicin (DOX) loaded smart liposome, MC‐T‐DOX, is constructed, that carries appropriately low‐density cilengitide, an αvβ3 integrin...

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Detalles Bibliográficos
Autores principales: Wei, Yan, Song, Sha, Duan, Nianxiu, Wang, Feng, Wang, Yuxi, Yang, Yiwei, Peng, Chengyuan, Li, Junjun, Nie, Di, Zhang, Xinxin, Guo, Shiyan, Zhu, Chunliu, Yu, Miaorong, Gan, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507343/
https://www.ncbi.nlm.nih.gov/pubmed/32995113
http://dx.doi.org/10.1002/advs.201902746