Higher CSF sTREM2 and microglia activation are associated with slower rates of beta‐amyloid accumulation

Microglia activation is the brain's major immune response to amyloid plaques in Alzheimer's disease (AD). Both cerebrospinal fluid (CSF) levels of soluble TREM2 (sTREM2), a biomarker of microglia activation, and microglia PET are increased in AD; however, whether an increase in these bioma...

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Detalles Bibliográficos
Autores principales: Ewers, Michael, Biechele, Gloria, Suárez‐Calvet, Marc, Sacher, Christian, Blume, Tanja, Morenas‐Rodriguez, Estrella, Deming, Yuetiva, Piccio, Laura, Cruchaga, Carlos, Kleinberger, Gernot, Shaw, Leslie, Trojanowski, John Q, Herms, Jochen, Dichgans, Martin, Brendel, Matthias, Haass, Christian, Franzmeier, Nicolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507349/
https://www.ncbi.nlm.nih.gov/pubmed/32790063
http://dx.doi.org/10.15252/emmm.202012308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507349/
https://www.ncbi.nlm.nih.gov/pubmed/32790063
http://dx.doi.org/10.15252/emmm.202012308

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