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Development of a novel cognitive composite outcome to assess therapeutic effects of exercise in the EXERT trial for adults with MCI: The ADAS‐Cog‐Exec

INTRODUCTION: Use of cognitive composites as primary outcome measures is increasingly common in clinical trials of preclinical and prodromal Alzheimer's disease (AD). Composite outcomes can decrease intra‐individual variability, resulting in improved sensitivity to detect longitudinal change an...

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Detalles Bibliográficos
Autores principales: Jacobs, Diane M., Thomas, Ronald G., Salmon, David P., Jin, Shelia, Feldman, Howard H., Cotman, Carl W., Baker, Laura D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507362/
https://www.ncbi.nlm.nih.gov/pubmed/32995469
http://dx.doi.org/10.1002/trc2.12059