Lupus IgG deposition causes arthritis but inhibits bone destruction through competitive occupation of FcγRI and reduced RANKL signalling

OBJECTIVES: Bone destruction is a remarkable feature of inflammatory arthritis. It remains unknown why arthritis associated with the systemic autoimmune/inflammatory condition systemic lupus erythematosus (SLE) does not result in erosion and destruction. We aimed to determine the role of autoantibod...

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Detalles Bibliográficos
Autores principales: Qiao, Wei, Ding, Huimin, Zuo, Yuyue, Jiang, Lijuan, Zhou, Jiayuan, Han, Xiaoxiao, Yu, Likai, Du, Rong, M Hedrich, Christian, Deng, Guo‐Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507387/
https://www.ncbi.nlm.nih.gov/pubmed/32994999
http://dx.doi.org/10.1002/cti2.1174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507387/
https://www.ncbi.nlm.nih.gov/pubmed/32994999
http://dx.doi.org/10.1002/cti2.1174

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