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Lupus IgG deposition causes arthritis but inhibits bone destruction through competitive occupation of FcγRI and reduced RANKL signalling
OBJECTIVES: Bone destruction is a remarkable feature of inflammatory arthritis. It remains unknown why arthritis associated with the systemic autoimmune/inflammatory condition systemic lupus erythematosus (SLE) does not result in erosion and destruction. We aimed to determine the role of autoantibod...
Autores principales: | Qiao, Wei, Ding, Huimin, Zuo, Yuyue, Jiang, Lijuan, Zhou, Jiayuan, Han, Xiaoxiao, Yu, Likai, Du, Rong, M Hedrich, Christian, Deng, Guo‐Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507387/ https://www.ncbi.nlm.nih.gov/pubmed/32994999 http://dx.doi.org/10.1002/cti2.1174 |
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