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NUP98‐HOXA10hd fusion protein sustains multi‐lineage haematopoiesis of lineage‐committed progenitors in transplant setting

OBJECTIVES: Exploring approaches of extending the haematopoiesis time window of MPPs and lineage‐committed progenitors might produce promising therapeutic effects. NUP98‐HOXA10hd (NA) fusion protein can expand long‐term haematopoietic stem cells (HSCs) and promote engraftment competitiveness without...

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Detalles Bibliográficos
Autores principales: Dong, Yong, Wang, Kaitao, Weng, Qitong, Wang, Tongjie, Zhou, Peiqing, Liu, Xiaofei, Geng, Yang, Liu, Lijuan, Wu, Hongling, Wang, Jinyong, Du, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507399/
https://www.ncbi.nlm.nih.gov/pubmed/32725842
http://dx.doi.org/10.1111/cpr.12885