Systematic analysis of bypass suppression of essential genes

Essential genes tend to be highly conserved across eukaryotes, but, in some cases, their critical roles can be bypassed through genetic rewiring. From a systematic analysis of 728 different essential yeast genes, we discovered that 124 (17%) were dispensable essential genes. Through whole‐genome seq...

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Detalles Bibliográficos
Autores principales: van Leeuwen, Jolanda, Pons, Carles, Tan, Guihong, Wang, Jason Zi, Hou, Jing, Weile, Jochen, Gebbia, Marinella, Liang, Wendy, Shuteriqi, Ermira, Li, Zhijian, Lopes, Maykel, Ušaj, Matej, Dos Santos Lopes, Andreia, van Lieshout, Natascha, Myers, Chad L, Roth, Frederick P, Aloy, Patrick, Andrews, Brenda J, Boone, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507402/
https://www.ncbi.nlm.nih.gov/pubmed/32939983
http://dx.doi.org/10.15252/msb.20209828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507402/
https://www.ncbi.nlm.nih.gov/pubmed/32939983
http://dx.doi.org/10.15252/msb.20209828

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