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Estrogen improved the regeneration of axons after subcortical axon injury via regulation of PI3K/Akt/CDK5/Tau pathway

AIM: To investigate the effect of estrogen on axon regeneration and neurological recovery after subcortical axon injury, and further explore its underlying molecular mechanisms. METHOD: Subcortical axonal fiber injury model was used in this study. Morris water maze was conducted to detect the learni...

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Detalles Bibliográficos
Autores principales: Xia, Xiaohui, Zhou, Changlong, Sun, Xiaochuan, He, Xuenong, Liu, Chang, Wang, Guanyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507494/
https://www.ncbi.nlm.nih.gov/pubmed/32755041
http://dx.doi.org/10.1002/brb3.1777